Think melatonin is safe? New research reveals a hidden heart risk

Think Melatonin Is Safe? New Research Reveals a Hidden Heart Risk

Recent findings suggest that long-term use of melatonin for sleep issues may carry serious cardiovascular risks. According to research, people who regularly take the supplement are almost twice as likely to die and 3.5 times more likely to be hospitalized for heart failure.

New Concerns from Heart Experts

Although melatonin is generally considered harmless, experts now advise caution with extended use. A study presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans indicated that adults suffering from chronic insomnia who used melatonin for at least a year faced increased risks of heart failure and death compared to non-users.

“The findings will be discussed at the AHA’s annual meeting, taking place Nov. 7–10 in New Orleans, a leading international event for cardiovascular science and clinical research updates.”

What Melatonin Does

Melatonin, a hormone produced by the pineal gland, helps regulate the sleep–wake rhythm. Its natural production rises at night and falls during daylight. Synthetic melatonin, identical to the body’s version, is commonly used to alleviate insomnia or jet lag.

Availability and Regulation

In countries like the United States, melatonin supplements are sold over the counter without prescription. However, since they are not strictly regulated, their purity and dosage can vary substantially between brands and batches.

Author’s Summary

Emerging evidence links long-term melatonin use with an elevated risk of heart failure, prompting experts to recommend moderation and medical guidance before extended consumption.

ScienceDaily — 2025-11-05