Indianapolis aims to overpower Atlanta's depleted offensive line and recover with strong performances from Jonathan Taylor and a tough defense. Despite the Falcons' efforts, their defensive setup with smaller pass rushers has proven vulnerable to the run, which benefits the Colts' strategy to control the game through the line of scrimmage on both sides.
"I trust [the Colts] to bounce back after a disappointing loss to the Pittsburgh Steelers."
Where to Bet: Indianapolis Colts -6.5 spread, -105 at ESPN Bet
2025 NFL Season Betting Record: 15-22
Summary: The Colts’ strong offensive line and Jonathan Taylor’s elite running skills provide a clear advantage over the Falcons, who face injuries and travel difficulties.