Leptin Neural Circuit Restores Balance After Anxiety Upsets It
Research has shown that a brain circuit involving leptin helps mice execute vital behaviors even when anxious.
A study led by researchers at the University of Cologne and University Hospital Cologne has identified the neural circuit that counteracts anxiety, helping mice perform essential behaviors and reduce maladaptive behaviors.
They found that neurons receptive to leptin – a hormone that governs energy balance in the body – track and predict anxiety, suppressing it to maintain balance.
Anxiety is an important mental state that helps protect us from dangerous situations; however, it can prevent us from eating, exploring new areas or resting appropriately.
This research could inform the treatment of anxiety-related psychiatric disorders in the future.
Author's summary: Leptin neural circuit helps mice with anxiety.
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